Article Type: Original Article

Title:  Comparison of addition of either dexamethasone or dexmedetomidine to caudal ropivacaine for Post-Operative analgesia after Paediatric Circumcision: A Randomized Controlled Study

Year: 2021; Volume: 1; Issue: 1; Page No: 3 – 7
Authors:  Smyrna Gnanasekaran1, Mohana Rangam Thirupathi2, Ashok Kulasekar3

Affiliations: 1Senior Resident, Department of Anesthesiology, Chettinad Hospital And Research Institute, Chennai, Tamilnadu, India.  2Assistant Professor, Department of Anesthesiology, Chettinad Hospital And Research Institute, Chennai, Tamilnadu, India.  3Professor and HOD, Department of Anesthesiology, Chettinad Hospital And Research Institute, Chennai, Tamilnadu, India.

Abstract:

Background: Over recent years, there are lots of advancements in providing adequate postoperative analgesia for pediatric patients who are undergoing infra-umbilical surgeries. Of which, the caudal block is a type of neuraxial block that is simple, easy to administer with more reliability, thus providing a very effective pain–free period. This study aimed to compare the efficacy of Ropivacaine with dexmedetomidine and dexamethasone in pediatric circumcision surgeries. 

Materials and Methods: The prospective, randomized, double-blinded study included 60 children (30 children in each group, assigned by computer-generated randomization code). In Group I: 0.25% Ropivacaine 0.5 ml/kg + Dexmedetomidine 1mcg/kg. Group II: 0.25% Ropivacaine 0.5 ml/kg + Dexamethasone 0.1 mg/kg.

Results: FLACC score was used to assess the postoperative analgesia. The mean duration of postoperative analgesia was 478.04±61.22min in the Dexmedetomidine group and 530.07±134.04 min in the Dexamethasone group which was statistically significant. The sedation score was better with Dexmedetomidine Group compared to Group Dexamethasone.

Conclusion: Our study proved that caudal administration of 0.25% Ropivacaine with Dexamethasone (0.1 mg/kg) resulted in a longer duration (530.07 minutes) of action compared with 0.25% Ropivacaine with Dexmedetomidine (1 mcg/ kg) and the sedation was better with Dexmedetomidine when compared to dexamethasone, without any other significant differences in the hemodynamic parameters and the incidence of adverse events.

Keywords: Caudal, Analgesia, Postoperative, Ropivacaine, Dexamethasone, Dexmedetomidine

Source of funding: We didn’t get any types of financial support from any financial organization;
Conflict of Interest:  The authors declared no conflict of interest

Corresponding Author:
Dr. Mohana Rangam Thirupathi,
Chettinad Hospital And Research Institute,
Rajiv Gandhi Salai OMR,
Kelampakkam, Chennai, Tamil Nadu.
Email ID:
drtmr79@gmail.com

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